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  1. You can take Glucophage (Metformin) with a meal unless your doctor specifies not. This is buy glucophage in oakland not harmful and will not affect the way glucophage XR works to control your diabetes. Glucophage (Metformin generic) is contraindicated in patients with chronic kidney disease, chronic liver disease, acute buy glucophage in oakland myocardial infarction, hypersensitivity to metformin or any excipients, and for patients with acute metabolic acidosis.